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1

Dichloroacetate metabolically targeted therapy defeats cytotoxicity of standard anticancer drugs

Dirk Heshe, Stephanie Hoogestraat, Christine Brauckmann, Uwe Karst, Joachim Boos, Claudia Lanvers-Kaminsky

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 643 KB

english, 2011

2

In vitro screening of plant extracts traditionally used as cancer remedies in Ghana â 15-Hydroxyangustilobine A as the active principle in Alstonia boonei leaves

Spiegler, Verena, Greiffer, Luise, Jacobtorweihen, Joshua, Asase, Alex, Lanvers-Kaminsky, Claudia, Hempel, Georg, Agyare, Christian, Hensel, Andreas

Journal:

Journal of Ethnopharmacology

Year:

2021

File:

PDF, 4.43 MB

2021

3

Drug-induced ototoxicity: Mechanisms, Pharmacogenetics, and protective strategies

Lanvers-Kaminsky, C, Zehnhoff-Dinnesen, AG am, Parfitt, R, Ciarimboli, G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 1003 KB

english, 2017

4

Pharmacogenetics of drug-induced ototoxicity caused by aminoglycosides and cisplatin

Lanvers-Kaminsky, Claudia, Ciarimboli, Giuliano

Journal:

Pharmacogenomics

Year:

2017

Language:

english

File:

PDF, 743 KB

english, 2017

5

Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood

Sarah E. Furchert, Claudia Lanvers-Kaminsky, Heribert Juürgens, Manfred Jung, Adele Loidl, Michael C. Frühwald

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 506 KB

english, 2007

6

Effects of telomerase inhibition and activation in neuroblastoma cell lines SKNSH and CHLA90

Y. Braun, K.-L. Schäfer, C. Lanvers-Kaminsky, A. Schuck, K. Brachwitz, R. Diallo, D. Gödde, H.E. Gabbert, C. Poremba

Journal:

Pathology - Research and Practice

Year:

2004

Language:

english

File:

PDF, 135 KB

english, 2004

7

Association of telomerase activity with radio- and chemosensitivity of neuroblastomas

Simone Wesbuer, Claudia Lanvers-Kaminsky, Ines Duran-Seuberth, Tobias Bölling, Karl-Ludwig Schäfer, Yvonne Braun, Normann Willich, Burkhard Greve

Journal:

Radiation Oncology

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

8

Serum asparaginase activities and asparagine concentrations in the cerebrospinal fluid after a single infusion of 2,500 IU/m2 PEG asparaginase in children with ALL treated according to protocol COALL-06-97

J.P. Vieira Pinheiro, K. Wenner, G. Escherich, C. Lanvers-Kaminsky, G. Würthwein, G. Janka-Schaub, J. Boos

Journal:

Pediatric Blood & Cancer

Year:

2006

Language:

english

File:

PDF, 198 KB

english, 2006

9

Continuous or repeated prolonged cisplatin infusions in children: A prospective study on ototoxicity, platinum concentrations, and standard serum parameters

C. Lanvers-Kaminsky, B. Krefeld, A.G. Dinnesen, D. Deuster, E. Seifert, G. Würthwein, U. Jaehde, A.C. Pieck, J. Boos

Journal:

Pediatric Blood & Cancer

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

10

Therapeutic drug monitoring of asparaginase in the ALL-BFM 2000 protocol between 2000 and 2007

Dominik Schrey, Stephan Borghorst, Claudia Lanvers-Kaminsky, Georg Hempel, Joachim Gerß, Anja Möricke, Martin Schrappe, Joachim Boos

Journal:

Pediatric Blood & Cancer

Year:

2010

Language:

english

File:

PDF, 161 KB

english, 2010

11

Five-year single-center study of asparaginase therapy within the ALL-BFM 2000 trial

Dominik Schrey, Katharina Speitel, Claudia Lanvers-Kaminsky, Joachim Gerss, Anja Möricke, Joachim Boos

Journal:

Pediatric Blood & Cancer

Year:

2011

Language:

english

File:

PDF, 456 KB

english, 2011

12

A population pharmacokinetic model for pegylated-asparaginase in children

Georg Hempel, Hans-Joachim Müller, Claudia Lanvers-Kaminsky, Gudrun Würthwein, Antje Hoppe, Joachim Boos

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 490 KB

english, 2010

13

No evidence of increased asparagine levels in the bone marrow of patients with acute lymphoblastic leukemia during asparaginase therapy

Wing H. Tong, Rob Pieters, Wim C.J. Hop, Claudia Lanvers-Kaminsky, Joachim Boos, Inge M. van der Sluis

Journal:

Pediatric Blood & Cancer

Year:

2012

Language:

english

File:

PDF, 101 KB

english, 2012

14

Microarray analysis of Ewing’s sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy

Karl-Ludwig Schaefer, Martin Eisenacher, Yvonne Braun, Kristin Brachwitz, Daniel H. Wai, Uta Dirksen, Claudia Lanvers-Kaminsky, Heribert Juergens, David Herrero, Sabine Stegmaier, Ewa Koscielniak, Ang

Journal:

European Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

15

Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

Giuliano Ciarimboli, Dirk Deuster, Arne Knief, Michael Sperling, Michael Holtkamp, Bayram Edemir, Hermann Pavenstädt, Claudia Lanvers-Kaminsky, Antoinette am Zehnhoff-Dinnesen, Alfred H. Schinkel, Her

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1018 KB

english, 2010

16

253 Anti-tumor Activity of the PLK Inhibitor Volasertib (BI 6727) and the Aurora Kinase Inhibitor BI 811283 in Pediatric Malignancies

Lanvers-Kaminsky, C., Abbou, S., Daudigeos-Dubus, E., Molenaar, J., Verschuur, A., Caron, H., Vassal, G., Geoerger, B.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 61 KB

english, 2012

17

Influence of cimetidine and its metabolites on Cisplatin—Investigation of adduct formation by means of electrochemistry/liquid chromatography/electrospray mass spectrometry

Brauckmann, Christine, Faber, Helene, Lanvers-Kaminsky, Claudia, Sperling, Michael, Karst, Uwe

Journal:

Journal of Chromatography A

Year:

2013

Language:

english

File:

PDF, 752 KB

english, 2013

18

Evaluation of Pharmacogenetic Markers to Predict the Risk of Cisplatin-Induced Ototoxicity

Lanvers-Kaminsky, C, Malath, I, Deuster, D, Ciarimboli, G, Boos, J, am Zehnhoff-Dinnesen, A G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 275 KB

english, 2014

19

Cytotoxicity of Dimethylacetamide and Pharmacokinetics in Children Receiving Intravenous Busulfan

Hempel, G., Oechtering, D., Lanvers-Kaminsky, C., Klingebiel, T., Vormoor, J., Gruhn, B., Boos, J.

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

20

Immediate Cooling Does Not Prevent the Ex Vivo Hydrolysis of L-Asparagine by Asparaginase

Lanvers-Kaminsky, Claudia, Westhoff, Petra Schulze, DʼIncalci, Maurizio, Zucchetti, Massimo, Boos, Joachim

Journal:

Therapeutic Drug Monitoring

Year:

2014

Language:

english

File:

PDF, 191 KB

english, 2014

21

Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity

Lanvers-Kaminsky, Claudia, Sprowl, Jason A, Malath, Ingrid, Deuster, Dirk, Eveslage, Maria, Schlatter, Eberhard, Mathijssen, Ron HJ, Boos, Joachim, Jürgens, Heribert, am Zehnhoff-Dinnesen, Antionette

Journal:

Pharmacogenomics

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

22

Population Pharmacokinetics of Liposomal Amphotericin B and Caspofungin in Allogeneic Hematopoietic Stem Cell Recipients

Wurthwein, G., Young, C., Lanvers-Kaminsky, C., Hempel, G., Trame, M. N., Schwerdtfeger, R., Ostermann, H., Heinz, W. J., Cornely, O. A., Kolve, H., Boos, J., Silling, G., Groll, A. H.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

23

Randomized Comparison of Safety and Pharmacokinetics of Caspofungin, Liposomal Amphotericin B, and the Combination of Both in Allogeneic Hematopoietic Stem Cell Recipients

Groll, A. H., Silling, G., Young, C., Schwerdtfeger, R., Ostermann, H., Heinz, W. J., Gerss, J., Kolve, H., Lanvers-Kaminsky, C., Vieira Pinheiro, J. P., Gammelin, S., Cornely, O. A., Wuerthwein, G.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

24

Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors

Arnhold, Viktor, Boos, Joachim, Lanvers-Kaminsky, Claudia

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.04 MB

english, 2016

25

Cytotoxic effects of novel polyoxotungstates and a platinum compound on human cancer cell lines

Gerth, Hans U. V., Rompel, Annette, Krebs, Bernt, Boos, Joachim, Lanvers-Kaminsky, Claudia

Journal:

Anti-Cancer Drugs

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005

26

In vitro toxicity of bisphosphonates on human neuroblastoma cell lines

Vorotnjak, Marta, Boos, Joachim, Lanvers-Kaminsky, Claudia

Journal:

Anti-Cancer Drugs

Year:

2004

Language:

english

File:

PDF, 449 KB

english, 2004

27

In-vitro toxicity of Ukrain against human Ewing tumor cell lines

Lanvers-Kaminsky, Claudia, Nolting, Dorothea-Maria, K??ster, Julia, Schr??der, Anke, Sandk??tter, Julia, Boos, Joachim

Journal:

Anti-Cancer Drugs

Year:

2006

Language:

english

File:

PDF, 593 KB

english, 2006

28

Cytotoxicity of treosulfan and busulfan on pediatric tumor cell lines

Lanvers-Kaminsky, Claudia, Bremer, Alexis, Dirksen, Uta, J??rgens, Heribert, Boos, Joachim

Journal:

Anti-Cancer Drugs

Year:

2006

Language:

english

File:

PDF, 106 KB

english, 2006

29

Systematic analysis of the antiproliferative effects of novel and standard anticancer agents in rhabdoid tumor cell lines

Lünenbürger, Henning, Lanvers-Kaminsky, Claudia, Lechtape, Birgit, Frühwald, Michael C.

Journal:

Anti-Cancer Drugs

Year:

2010

Language:

english

File:

PDF, 254 KB

english, 2010

30

An in-vitro evaluation of the polo-like kinase inhibitor GW843682X against paediatric malignancies

Spaniol, Kristina, Boos, Joachim, Lanvers-Kaminsky, Claudia

Journal:

Anti-Cancer Drugs

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

31

CLINICAL TRIALS AND OBSERVATIONS A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia

Tong, Wing H, Pieters, Rob, Kaspers, Gertjan J L, Loo, D Maroeska W M, Bierings, Marc B, Bos, Cor Van Den, Kollen, Wouter J W, Hop, Wim C J, Lanvers-kaminsky, Claudia, Relling, Mary V, Tissing, Wim J

Year:

2015

Language:

english

File:

PDF, 1.26 MB

english, 2015

32

Asparaginase pharmacology: challenges still to be faced

Lanvers-Kaminsky, Claudia

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2017

Language:

english

File:

PDF, 994 KB

english, 2017

33

Population Pharmacokinetics to Model the Time-Varying Clearance of the PEGylated Asparaginase Oncaspar® in Children with Acute Lymphoblastic Leukemia

Würthwein, Gudrun, Lanvers-Kaminsky, Claudia, Hempel, Georg, Gastine, Silke, Möricke, Anja, Schrappe, Martin, Karlsson, Mats O., Boos, Joachim

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 687 KB

english, 2017

34

Therapeutic Drug Monitoring of Asparaginase Activity - Method Comparison of MAATTM and AHA Test Used in the International AIEOP-BFM ALL 2009 Trial

Lanvers-Kaminsky, Claudia, Rüffer, Andrea, Würthwein, Gudrun, Gerss, Joachim, Zucchetti, Massimo, Ballerini, Andrea, Attarbaschi, Andishe, Smisek, Petr, Nath, Christa, Lee, Samiuela, Elitzur, Sara, Zi

Journal:

Therapeutic Drug Monitoring

Year:

2017

Language:

english

File:

PDF, 2.56 MB

english, 2017

35

Preclinical Evaluation of Combined Topoisomerase and Proteasome Inhibition Against Pediatric Malignancies

DESTANOVIC, EDVIN, BOOS, JOACHIM, LANVERS-KAMINSKY, CLAUDIA

Journal:

Anticancer research

Year:

2018

Language:

english

File:

PDF, 238 KB

english, 2018

36

Asparaginase activities during intensified treatment with pegylated E. coli asparaginase in adults with newly-diagnosed acute lymphoblastic leukemia

Lanvers-Kaminsky, Claudia, Niemann, Andreas, Eveslage, Maria, Beck, Joachim, Köhnke, Thomas, Martin, Sonja, de Wit, Maike, Spriewald, Bernd, Hauspurg, Holger, Hoelzer, Dieter, Boos, Joachim, Gökbuget,

Journal:

Leukemia and Lymphoma

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

37

Can we optimise doxorubicin treatment regimens for children with cancer? Pharmacokinetic simulations and a Delphi consensus procedure

Siebel, Christian, WÃ¼rthwein, Gudrun, Lanvers-Kaminsky, Claudia, AndrÃ©, Nicolas, Berthold, Frank, Castelli, Ilaria, Chastagner, Pascal, Doz, FranÃ§ois, English, Martin, Escherich, Gabriele, FrÃ¼hwal

Journal:

BMC Pharmacology and Toxicology

Year:

2020

File:

PDF, 935 KB

2020

38

Therapeutic Drug Monitoring of Asparaginase

WÃ¼rthwein, Gudrun, Lanvers-Kaminsky, Claudia, Gerss, Joachim, MÃ¶ricke, Anja, Zimmermann, Martin, Stary, Jan, Smisek, Petr, Attarbaschi, Andishe, Nath, Christa, Zucchetti, Massimo, Rizzari, Carmelo,

Journal:

Therapeutic Drug Monitoring

Year:

2020

File:

PDF, 586 KB

2020

39

Bioanalysis of doxorubicin aglycone metabolites in human plasma samplesâimplications for doxorubicin drug monitoring

Siebel, Christian, Lanvers-Kaminsky, Claudia, WÃ¼rthwein, Gudrun, Hempel, Georg, Boos, Joachim

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.36 MB

2020